Unlike animals, plants stably pass on their DNA methylomes from one generation to the next. The resulting gene silencing likely hides an abundance of phenotypic variation.
Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.
The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.
The challenges of adapting drug development to the age of personalized therapies encourage collaboration among industry players.