My Mighty Mouse

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

Mining the Outliers

Even when a clinical trial fails, some patients improve. What can researchers learn from these exceptional responders?

Cancer Kismet

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

Capsule Reviews

Junk DNA, Cuckoo, Sapiens, and Cool

Riding Out Rejection

How to navigate the choppy waters of scientific publication

News & Opinion

Covering the life sciences inside and out

image: Enzyme Improves CRISPR

Enzyme Improves CRISPR


A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

image: Hiding in Plain Sight

Hiding in Plain Sight


Researchers using metagenomics and single-cell sequencing identify a potential new bacterial phylum.

image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work


Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 

The Nutshell

Daily News Roundup

The “Genes for Good” Facebook app and the Open Humans Network plan to recruit large numbers of volunteers for medical studies using social media.

Microbial ecology of fermented foods; NASA twin study; new cleaning protocols for superbug-associated scope

The US National Institutes of Health has formed a team of experts to begin the process of building President Obama’s Precision Medicine Initiative.

Inhibitory nerve cells in the spinal cord stop the transmission of pain and itch signals in mice.

Current Issue

April 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.

Scientists make oxygen-filled microbubbles designed to increase tumor sensitivity to radiation.


Video, Slideshows, Infographics

Cornell researchers probe the brains of jumping spiders to gain insight into the arachnid's visual processing capabilities.

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

The Marketplace

New Product Press Releases

More than 50% lighter than conventional racks, yet don't compromise on strength and are completely recyclable.

Enables More Informed Casework Decisions.

Software provides simple but powerful solution for designing CRISPR experiments.

mRNA-In™ and mRNA-In™ Neuro – a new range of high efficiency, targeted transfection reagents.

Nanolive SA 3D Cell Explorer

Nanolive SA announces the release of an off-­line version of STEVE.

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Bethyl Laboratories

Featured Comment

Marie-Paule Kieny started off her comment oh so right, but then continued oh so wrong.  In this case, forget the bioethicists. Kieny should have said, "We need to tell the bioethicists that there is no other choice."

- Unknown, Bioethics of Experimental Ebola Treatments