Grab ’n’ Glow

Engineered proteins can tether multiple fluorescent molecules to give a brighter signal—and that’s not all.

Tangle Trigger

An enzyme that cleaves tau protein in acidic cellular conditions may trigger early events in Alzheimer’s disease.

May the Best Rodent Win

Are mice, considered by some to be the less intelligent rodent, edging out rats as laboratory models of decision making?

Caught on Camera

Selected Images of the Day

Crossed Wires

From similar sets of neuroimaging data, researchers are reaching different conclusions about whether brain wiring differs between men and women.

The Sex Parts of Plants, 1736

Carl Linnaeus’s plant classification system was doomed, and he knew it.

Straighten Out

Forces from bidirectional growth plates mechanically realign broken bones in infant mice.

Eye on the Fly

Automating Drosophila behavior screens gives researchers a break from tedious observation, and enables higher-throughput, more-quantitative experiments than ever before.

News & Opinion

Covering the life sciences inside and out

A mass migration of mobile regulatory elements increased the expression of thousands of genes in the uterus during the evolution of pregnancy.

Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.

image: Brain Cells Behind Overeating

Brain Cells Behind Overeating


Scientists have defined neurons responsible for excessive food consumption at an unprecedented level of detail. 

image: Sonic Experiment

Sonic Experiment


An artist takes advantage of muscle-mimicking polymers to manipulate sounds.

The Nutshell

Daily News Roundup

Charles Townes, Nobel Prize-winning physicist, has passed away at age 99.

Celebrating lab techs; Myriad settles suits; publish in top-tier journals or perish

Scientists uncover early evidence of modern man’s movements from Africa into Europe—and of potential human-Neanderthal interbreeding.

Using ultraviolet light to disinfect drinking water may simply drive bacteria to dormancy, rather than kill them.

Current Issue

January 2015

In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.

Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.

Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.

A new way of evaluating academics’ research output using easily obtained data


Video, Slideshows, Infographics

How DuPont uses CRISPR to keep yogurt and cheeses safe from bacteriophage attack

The artful science of Tom Deerinck, a micrographer who consistently places in Nikon’s Small World competition

The Marketplace

New Product Press Releases

The omniDOC series provides researchers with a quick, simple and flexible solution for their gel documentation needs.

Thermal Lab Beads Replace Water/Ice in Lab Baths

An all new high performance medium throughput synthesizer.

The Micronic Tracxer TS201 MINI is a new high-speed storage tube code reader.

INTEGRA has expanded its popular VIAFLO II electronic pipette range.

Unmatched Reproducibility to Kinetex® HPLC/UHPLC Core-Shell Line

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Featured Comment

Marie-Paule Kieny started off her comment oh so right, but then continued oh so wrong.  In this case, forget the bioethicists. Kieny should have said, "We need to tell the bioethicists that there is no other choice."

- Unknown, Bioethics of Experimental Ebola Treatments