Thanks for the Memories

B and T cells may be the memory masters of the immune system, but research reveals that other cells can be primed by pathogens, too.

Nibbled? No Problem

Making extra copies of their genomes allows some plants to better withstand damage.

Time-Lapse on the Cheap

A PhD student jury-rigs a microscopy system for high-throughput cell motility assays.

Centennial Shigella

A strain of the dysentery-causing bacterium isolated in 1915 tells the story of a young soldier who died of the disease in the early days of World War I.

Lazarus Drugs

While some drugs sail through development, others suffer setbacks, including FDA rejections, before reaching the market.

Scientific Publishing, 1665

Henry Oldenburg founded Philosophical Transactions to share scholarly news from the “Ingenious in many considerable parts of the World.”

Screening Goes In Silico

Computational tools take some of the cost—and guesswork—out of drug discovery.

TSLive: The Enemy Within

How viruses wield tiny molecules of RNA to help them persist in our bodies for years, decades, and sometimes an entire life span

News & Opinion

Covering the life sciences inside and out

image: Evolutionary Rewiring

Evolutionary Rewiring


Strong selective pressure can lead to rapid and reproducible evolution in bacteria.

image: Stem Cells Phone Home

Stem Cells Phone Home


A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.

Advances in genome-editing technologies have made modifying crops easier than ever before. They’ve also clouded the already murky realm of genetically modified foods.

Researchers report an association between culture conditions and genetic changes in stem cells over time.

The Nutshell

Daily News Roundup

A former Iowa State University researcher faces up to 10 years in prison for faking data involving a study of an HIV vaccine.

GM animals; citizen-scientists; strange standard reference materials

The British House of Lords has approved new rules regarding the creation of embryos using genetic material from three donors.

Mammalian eyelashes are the optimal length for protecting eyes from dust and drying out, a study suggests.

Current Issue

February 2015

B and T cells may be the memory masters of the immune system, but research reveals that other cells can be primed by pathogens, too.

Extremophiles should not be viewed through an anthropocentric lens; what’s extreme for us may be a perfectly comfortable environment for a microbe.

New understanding of noncoding RNAs may solve a long-standing puzzle about how viruses orchestrate lifelong infections.  

Gut bacteria in mice spur regulatory B cells to differentiate and release an anti-inflammatory cytokine.


Video, Slideshows, Infographics

Take a tour of deep-sea methane seeps and meet the organisms that call these extreme environments home.

See how scallop locomotion informed the design of a microscopic robot that could one day navigate our circulatory systems.

The Marketplace

New Product Press Releases

Molecular Devices Launches No-Wash Potassium Ion Channel Assay Kit.

MP Biomedicals, Leading Life Science and Diagnostics Product Provider, Launches new Automated Nucleic Acid Purification Platform – MPure-12.

Eppendorf Announces New BioFlo® 320 Bench Scale Bioprocess Control Station.

INTEGRA Biosciences has launched PIPETGIRL - a new pink version of its popular PIPETBOY acu 2 pipette controller.

Oxford Instruments shines a new light on optical spectroscopy.

Automated Incubator Can Now Be Monitored, Controlled from Virtually Anywhere.

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Featured Comment

Marie-Paule Kieny started off her comment oh so right, but then continued oh so wrong.  In this case, forget the bioethicists. Kieny should have said, "We need to tell the bioethicists that there is no other choice."

- Unknown, Bioethics of Experimental Ebola Treatments