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The Body Sleeps, but the Genes Do Not
Everyone does it, but no one knows why; a sleep-gene survey may offer clues
The Scientist 2004, 18(3):24
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In a study that could offer a glimpse into sleep's still poorly understood functions, researchers have identified genes upregulated specifically during sleep.[1]
The findings contain surprises, investigators say. One is simply that there are many such genes, at least as many as are turned on while awake, belying the common-sense view that sleep implies inactivity. Another is that the sleep-related changes in gene expression extend to the cerebellum, a structure not previously known to participate in sleep.
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