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How It Works | Yeast Two-Hybrid Assay
The Scientist 2005, 19(16):34
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The ultimate realization of the yeast two-hybrid (Y2H) assay is the interactome. In theory, an interactome is a proteome-wide map of a cell's protein-protein interactions. In practice, they represent a mere fraction of possible protein couplets. Nevertheless, these charts of cell machinery have provided critical insights into protein behavior and function, largely thanks to the Y2H assay.
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