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by Linda Sage

TOOLS AND TECHNOLOGY

Deciphering Drug Mechanisms
Novel method reveals how drugs affect a wide range of cellular processes


The Scientist 2005, 19(2):34

Published 31 January 2005

A team of Harvard scientists has found a high-throughput way to tie drugs with the cellular functions they affect.[1] Comparing the profiles of uncharacterized compounds with those of well-studied ones, the group also predicted modes of action. The study employed a combination of fluorescent probes, high-throughput microscopy, automated image analysis, and advanced statistics.


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