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Deciphering Drug Mechanisms
Novel method reveals how drugs affect a wide range of cellular processes
The Scientist 2005, 19(2):34
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A team of Harvard scientists has found a high-throughput way to tie drugs with the cellular functions they affect.[1]
Comparing the profiles of uncharacterized compounds with those of well-studied ones, the group also predicted modes of action. The study employed a combination of fluorescent probes, high-throughput microscopy, automated image analysis, and advanced statistics.
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