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Battling Evolution to Fight Antibiotic Resistance
Fresh approaches could aid existing drugs
Email: Monya Baker - mbaker@the-scientist.com The Scientist 2005, 19(19):17
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For any new antibiotic, resistant bacteria typically show up in four years, or less. Penicillin resistance was reported clinically even before large-scale use of the antibiotic began in 1942. The battle against antibiotic-resistant bacteria demands new drugs and smarter, more responsible ways to use existing ones. Some researchers, however, are pursuing another type of weapon: drugs that sidestep natural selection. Less virulent bacteria would decrease the need for antibiotics, some reason, and drugs that drastically slow mutation rates might cut off evolution's power source.
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