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How Does Your Virus Grow?
As scientists develop culture methods for three important human viruses, what have we learned in the process?
Email: Erika Jonietz - ejonietz@the-scientist.com The Scientist 2005, 19(17):29
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Researchers at Chiron made virology history in 1987 when they discovered the hepatitis C virus (HCV), not by isolating viral particles, but by cloning and sequencing its genome. Subsequently, scientists developed tests for HCV infection and deciphered aspects of its lifecycle. But the virus has stubbornly resisted every attempt to grow it in vitro, leaving major parts of its biology inscrutable.
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