Applying chemical genetics to mice, Roger Davis at University of Massachusetts Medical School and the Howard Hughes Medical Institute, and colleagues found that JNK2 promotes phosphorylation and activation of cJun. 1 "It is an elegant and solid paper that illustrates the power of chemical genetics and it settles a controversy in the field," says Faculty of 1000 member Filippo Giancotti of Memorial Sloan-Kettering Cancer Center in New York.
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JNK2 promotes cJun activation
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