Much of the history of genetics and molecular biology was built using microorganisms such as Escherichia coli and Staphylococcus aureus. Yet these species are the exception, not the rule, in microbiology: Unlike the vast majority of microbes, they can be cultivated in the laboratory, grown in pure culture, and thus, dissected biochemically.
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The Big Picture in Microbial Genomics
A revolution aids the study of unculturable microorganisms
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