Model of Ubx activation refuted

For several years researchers thought that bithoraxoid noncoding RNAs (bxd ncRNAs) prevented the silencing of the Hox gene, Ultrabithorax, during Drosophila development. "If that's true, then the transcript for bxd should be expressed in the same cell as the transcript for Ubx," explains Faculty of 1000 member Pamela Geyer, a professor of Biochemistry at the University of Iowa. But recent experiments show that bxd transcripts aren't present in the same cells that expres Ubx transcripts.1

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