Hidden Markov Genomics

Asger Hobolth at North Carolina State University's Bioinformatics Research Center and his team used a hidden Markov model to estimate that chimps and humans diverged from a common ancestor only about 4.1 million years ago.1 Hobolth looked at the probability distribution of 1.9 billion DNA base pairs across humans, chimpanzees, gorillas, and orangutans, searching for differences in the historical sequences.


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