Alan Hinnebusch earned his scientific chops in the early 1980s, when yeast genetics, he says, was entering its golden age. At the time, Hinnebusch was a postdoc in the Cornell laboratory of Gerald Fink. "DNA transformation had just been developed in Gerry's lab," he says. That technique essentially allowed researchers to "isolate any gene, manipulate it, and put it back into the organism," making yeast "a eukaryote that you could study like Escherichia coli in terms of genetics."
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Alan Hinnebusch has worked doggedly through the years to figure out how yeast genes are regulated.
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