In 1885, pathologist George Elliott was looking through his microscope at the histological preparation of a tumor pictured here. He noted that "the structure is largely composed of epithelial tissue which in places appears in the form of distinct lobules or "cell nests." In spots the cells show a tendency to group and form concentric globes, which indicates that the cells have been rapidly forming." Based on his findings, Elliott diagnosed the tumor as "epithelioma of a squamous cell variety."
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Histology, circa 1885
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