Proteins almost never act alone. In a molecular version of "guilt by association," identifying the function of novel proteins often requires pinning down the proteins with which they interact. But yeast two-hybrid assays and coimmunoprecipitation, the two main techniques for generating "interactomes," maps of protein interactions on a proteome-wide scale, can leave gaping holes.
Advertisement
Survey Series
For Advertisers
Close Encounters
Protein-protein interaction assays for all occasions.
|
|||||||||
|
|||||||||
|
