Symmetric and Asymmetric Division Models :The Scientist [2008-02-01]


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	By Steven Reiner

Symmetric and Asymmetric Division Models How does the body produce the diversity in T-cell fates that are essential for immunity? The symmetric division model predicts that the fate of each naïve T-cell is determined by the cytokines the dendritic cell produces: one cell, one fate. The asymmetric division model predicts that two fates arise from a single na￯ve T-cell. The effector cells defend against the microbe, while the