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About Vern L. Schramm
Articles Posted by Vern L. Schramm
Designing Transition-State Inhibitors
Published: May 1, 2012
A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate the structure of an enzyme’s transition state, whic
Freezing Time
Published: May 1, 2012
Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.
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