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The Scientist

» mouse models

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image: Circadian Clock and Aging

Circadian Clock and Aging

By | February 3, 2016

Whether a critical circadian clock gene is deleted before or after birth impacts the observed aging-related effects in mice.

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image: Epigenetics of Obesity

Epigenetics of Obesity

By | January 29, 2016

Differential expression of a chromatin-interacting protein is linked to weight variation in mice and humans, researchers show.

1 Comment

image: Inside a Lab Mouse’s High-Fat Diet

Inside a Lab Mouse’s High-Fat Diet

By | November 23, 2015

Researchers should pay closer attention to the diets they use to study obesity in mice, experts advise.

5 Comments

image: Microbiome Meals

Microbiome Meals

By | October 1, 2015

Researchers identify a handful of genes that help bacteria in the mouse gut adapt to dietary changes.

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image: Neutrophils Lead, T Cells Follow

Neutrophils Lead, T Cells Follow

By | September 3, 2015

When influenza invades the mouse respiratory tract, neutrophils guide the subsequent T-cell attack on infected tissue, scientists show.  

2 Comments

image: Hormone Affects “Runner’s High”

Hormone Affects “Runner’s High”

By | September 2, 2015

Leptin, the satiety hormone produced by fat, affects neuronal signaling in the mouse brain; interference with this pathway can influence the rewarding effects of running in the animals.

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image: Double-Edged Enzyme

Double-Edged Enzyme

By | August 13, 2015

Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.

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image: The Human Touch

The Human Touch

By | August 1, 2015

Can mice with humanlike tissues better model drug effects in people?

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image: Resveratrol’s Low-Dose Anticancer Effect

Resveratrol’s Low-Dose Anticancer Effect

By | July 31, 2015

The antioxidant found in red wine and some berries shows that small doses have more potent antitumor effects than large doses in a mouse model.

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image: When Does a Smart Mouse Become Human?

When Does a Smart Mouse Become Human?

By | July 1, 2015

Ethical issues attend the creation of animal-human chimeras.

1 Comment

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