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» drug resistance and microbiology

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image: How a Popular Probiotic Works

How a Popular Probiotic Works

By | April 16, 2015

Eating a type of bacterium encourages the activity of other gut microbes, according to a small study.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

1 Comment

image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Soil Bacteria Live on Wine Grapes

Soil Bacteria Live on Wine Grapes

By | March 25, 2015

The earthiness of Merlot may have to do with grapevine-dwelling microbiota.

2 Comments

image: Quorum-Sensing Molecule Modifies Gut Microbiota

Quorum-Sensing Molecule Modifies Gut Microbiota

By | March 19, 2015

Increasing the abundance of a chemical some microbes use to communicate with one another can help reinstate beneficial bacterial populations in the guts of antibiotic-treated mice. 

1 Comment

image: Sewage Bacteria Linked to Obesity

Sewage Bacteria Linked to Obesity

By | March 10, 2015

Microbes identified in a city’s sewage treatment plants correlate with the population’s obesity rate, a study shows.

1 Comment

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