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image: Fat’s Influence on Cancer

Fat’s Influence on Cancer

By | April 3, 2017

Researchers at the annual American Association for Cancer Research meeting discuss the roles of adipose tissue and inflammation in the growth and spread of tumors.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Tracking the Evolutionary History of a Tumor

Tracking the Evolutionary History of a Tumor

By | April 1, 2017

Analyzing single cell sequences to decipher the evolution of a tumor

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image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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