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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Weathering Hantavirus: Ecological Monitoring Provides Predictive Model
Steve Bunk | Jul 4, 1999 | 7 min read
Photo: Steve Bunk Dave Tinnin, field research associate in the University of New Mexico's biology department, takes blood samples and measurements of rodents caught on the research station grounds. At the end of a freeway exit near Soccoro, N.M., the hairpin turn onto a gravel road is marked by a sign that warns, "Wrong Way." But it isn't the wrong way if you want to reach the University of New Mexico's (UNM) long-term ecological research (LTER) station. The sign's subterfuge is the first indi
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Notebook
The Scientist Staff | Apr 14, 1996 | 8 min read
SEEKING SHELTER: Surplus lab chimps need a place to stay. While no plans are under way to build them a golf course or shuffleboard court, a nonprofit organization has been established to create a "retirement home" for chimpanzees not needed in biomedical or behavioral research. Chimp Haven, a San Antonio, Texas-based group, aims to build a facility to provide long-term housing for the unneeded chimps. The United States has a surplus of chimpanzees bred for research purposes, a result of the s
Illuminating Behaviors
Douglas Steinberg | Jun 1, 2003 | 6 min read
Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t
A Living Legacy
Megan Scudellari | Jan 13, 2010 | 10 min read
A Living Legacy At the birthplace of stem cell research, the next generation of scientists continues to advance the field. By Megan Scudellari In Toronto’s downtown Discovery District, world-class stem cell researchers populate the buildings like athletes at the Olympics. On University Avenue, Andras Nagy, a renowned innovator in induced pluripotent stem (iPS) cells, works at the Samuel Lunenfeld Research Institute, housed within the towering Mount Sin
Woods Hole Lab Faces Uncertain Future
Elizabeth Pennisi | Aug 7, 1988 | 10 min read
Celebrating its centennial, the Marine Biological Laboratory adapts to a new era in which money talks as loudly as science WOODS HOLE, MASS.—When Harlyn 0. Halvorson, the new director of the Marine Biological Laboratory in Woods Hole, blows out the candles for his institution’s 100th birthday this summer, no one will have to ask what he wished for. The laboratory needs more money, more room, and more molecular biology if it is to remain in the forefront of scientific research durin

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