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Image of the Day: Cellular Breakdown
Image of the Day: Cellular Breakdown
Autophagy may keep cell division in check to help protect against cancer-causing DNA damage.
Image of the Day: Cellular Breakdown
Image of the Day: Cellular Breakdown

Autophagy may keep cell division in check to help protect against cancer-causing DNA damage.

Autophagy may keep cell division in check to help protect against cancer-causing DNA damage.

mutations, cell & molecular biology

Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017 | 8 min read
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
Mutations Not Tied to Metastasis
Kerry Grens | Feb 25, 2016 | 3 min read
Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.
Decoding Breast Cancer Drug Resistance
Ed Yong | Nov 3, 2013 | 4 min read
Common mutations in metastasized breast tumors suggest how the cancer can develop resistance to frontline drugs.
Gene Therapy Coming of Age?
Dan Cossins | Jul 11, 2013 | 4 min read
Using lentiviral vectors to replace mutated genes in blood stem cells, scientists successfully treat two rare diseases apparently without causing harmful side effects.
Sweet Smell of Success
Karen Hopkin | Jul 1, 2012 | 9 min read
With persistence and pluck, Leslie Vosshall managed to snatch insect odorant receptors from the jaws of experimental defeat.
The Tradeoff of Stress
Ruth Williams | Dec 15, 2011 | 3 min read
For nematode worms, a bigger stress response means a healthier, longer life, but fewer babies.
Our own 60 mutations
Jef Akst | Jun 15, 2011 | 1 min read
New estimates of human mutation suggest that each of us harbor approximately 60 novel genetic mutations.
Where Cancer and Inflammation Intersect
Giorgio Trinchieri | Apr 1, 2011 | 1 min read
Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 
Losers Fight Back
Richard P. Grant | Feb 1, 2011 | 2 min read
Editor's choice in developmental biology
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