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image: Fighting Viruses with RNAi

Fighting Viruses with RNAi

By | October 10, 2013

The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.

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image: RNAi Remedy Lowers Cholesterol

RNAi Remedy Lowers Cholesterol

By | October 3, 2013

A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.

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image: Gene Silencing Is Golden

Gene Silencing Is Golden

By | August 1, 2013

A beginner’s how-to on RNAi screening in mammalian cells

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image: Shushing RNA

Shushing RNA

By | August 1, 2013

The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.

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image: Why Women’s Eggs Don’t Last

Why Women’s Eggs Don’t Last

By | February 13, 2013

As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.

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image: Going Boldly Forth

Going Boldly Forth

By | January 1, 2013

Gregory Hannon believes in taking risks—an approach that’s enabled him to make exciting new discoveries in the world of small RNAs.

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image: Dynamic Delivery

Dynamic Delivery

By | July 1, 2012

Microscopic sponges made entirely of RNA enable efficient gene silencing.

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image: Interfering with Resistance

Interfering with Resistance

By | June 1, 2012

Drug efficacy and resistance mechanisms shine a light on how drugs enter cells, which could facilitate the development of new sleeping-sickness treatments. 

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image: Model Citizen

Model Citizen

By | March 1, 2012

With an eye to understanding animal regeneration, Alejandro Sánchez Alvarado has turned a freshwater planarian into a model system to watch.

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image: One Bad Apple

One Bad Apple

By | June 24, 2011

A unique virus and the worm it infects turn up in an orchard outside of Paris.

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