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Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

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A team of scientists was unable to replicate controversial, high-profile findings published in 2011.

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image: Exploring the Epigenetics of Ethnicity

Exploring the Epigenetics of Ethnicity

By | January 11, 2017

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

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image: Contributors

Contributors

By | January 1, 2017

Meet some of the people featured in the January 2017 issue of The Scientist.

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image: Newly Found White Blood Cell Withstands Chemotherapy

Newly Found White Blood Cell Withstands Chemotherapy

By | January 1, 2017

Vaccine-induced macrophages open a new realm of study into remodeling the immune system to reduce the risk of infections during cancer treatment.

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image: Pharma Redo

Pharma Redo

By | January 1, 2017

Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.

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image: RNA Sequences Don’t Predict In Vivo Transcript Structure

RNA Sequences Don’t Predict In Vivo Transcript Structure

By | January 1, 2017

Eukaryotes prevent secondary RNA structures called G-quadruplexes, commonly observed in vitro, from forming in the cell. 

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image: Transgenerational Epigenetics Prepares Plants for Drought

Transgenerational Epigenetics Prepares Plants for Drought

By | January 1, 2017

Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 

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image: Infographic: Examining Open Chromatin

Infographic: Examining Open Chromatin

By | January 1, 2017

See how researchers visualize regions of active genes.

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image: Infographic: Keeping RNA Structures in Line

Infographic: Keeping RNA Structures in Line

By | January 1, 2017

Scientists find fewer RNA G-quadruplexes in vivo than in vitro.

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