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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
A black-and-white photo of a person’s hands holding a black-and-white barred chicken. The feathers of its breast have been pulled back to reveal a large tumor.
Transmissible Tumors, 1909
Katherine Irving | Jan 2, 2023 | 2 min read
Pathologist Peyton Rous made a groundbreaking discovery in the early 20th century, but his work wasn’t widely recognized until more than 40 years later. 
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
a colorful ctenophore/comb jelly swimming
Genome Spotlight: California Sea Gooseberry (Hormiphora californensis)
Christie Wilcox, PhD | Nov 24, 2021 | 3 min read
The first chromosome-level genome assembly for a ctenophore may allow scientists to finally resolve the roots of the animal family tree.
Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
heath hen Tympanuchus cupido de-extinction grouse pgc germline transmission cultured germ cell transmission
The Booming Call of De-extinction
W. S. Roberts | Oct 19, 2020 | 6 min read
Scientists seek to combine genome editing with a technique used in chicken breeding to try to bring back lost birds.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.

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