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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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Another case of HIV remission emerges, this time in a South African girl diagnosed as an infant and disease-free for more than eight years.

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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Using single-cell RNA sequencing, scientists characterize new populations of dendritic cells and monocytes.

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image: Making the Rounds

Making the Rounds

By | July 17, 2017

Circular RNA biogenesis occurs when RNA fragments are bent into closed loops of one or more exons and/or introns.

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image: RNA Protects “Naked” Genomes from Retrotransposons

RNA Protects “Naked” Genomes from Retrotransposons

By | June 30, 2017

Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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image: T Cells That Drive Toxic Shock in Mice Identified

T Cells That Drive Toxic Shock in Mice Identified

By | June 20, 2017

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

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