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tag reprogramming neuroscience disease medicine

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A reprogrammed astrocyte that can regenerate functional neurons.
Reprogramming Astrocytes: Unlocking DLX2’s Potential to Mend the Brain
Nele Haelterman, PhD | Jan 23, 2023 | 3 min read
Scientists discover how to convert the brain’s glial cells into multipotent neural stem cells.
Glowing red DNA on bluish background
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018 | 10 min read
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Microscopy image of a fluorescent green oligodendrocyte surrounded by astrocytes stained red with blue nuclei.
Searching for a Direct Route to Multiple Sclerosis Treatment
Deanna MacNeil, PhD | Jul 17, 2023 | 3 min read
Researchers created a new high-throughput tool to hunt for therapies that remyelinate the nervous system.
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinsonā€™s
Diana Kwon | Apr 10, 2017 | 3 min read
By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.

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