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tag synapse formation microbiology neuroscience

Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
MIT Lab Retracts Paper
Dan Cossins | Feb 15, 2013 | 2 min read
A paper describing a new method for imaging synapse formation has been retracted after it emerged that the first author falsified data to prove its effectiveness.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
Sleep adjusts fly synapses
Bob Grant | Apr 1, 2009 | 3 min read
New findings support a controversial hypothesis about the biological role of sleep: Snoozing may be a way for the brain to clear clutter accumulated after a hard day of synapse forming and strengthening. Two __Science__ studies published today suggest that the brains of sleeping __Drosophila__ undergo an overall depression in synaptic strength and number, eliminating some minor neuronal connections while merely weakening stronger ones.Expression of synaptic markers is low aftersleep (left) and h
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
How Immune Cells Make the Brain Forget
Ashley Yeager | May 1, 2020 | 4 min read
Microglia ingest nerve cell connections, leading to the loss of information stored in neuronal circuits.
Week in Review: January 6–10
Tracy Vence | Jan 10, 2014 | 3 min read
Bacterial genes aid tubeworm settling; pigmentation of ancient reptiles; nascent neurons and vertebrate development; exploring simple synapses; slug-inspired surgical glue
Do Microbes Trigger Alzheimer’s Disease?
Jill U. Adams | Sep 1, 2017 | 10 min read
The once fringe idea is gaining traction among the scientific community.

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