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image: Trump Meets with HHS, NIH Brass

Trump Meets with HHS, NIH Brass

By | April 5, 2017

President Donald Trump, HHS Secretary Tom Price, and NIH Director Francis Collins discussed the opioid crisis and retaining young researchers in the biomedical research enterprise, among other things, according to a White House official.

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Both Democrats and Republications criticize the Trump administration’s plan to cut funding for biomedical research.

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image: TS Picks: April 3, 2017

TS Picks: April 3, 2017

By | April 3, 2017

USDA posting few animal inspections; HHS secretary proposes cutting indirect research expenses; science journalism vs. fake news

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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