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tag digital pcr neuroscience genetics genomics developmental biology

Molecule of DNA forming inside the test tube equipment.3d rendering,conceptual image.
EvaGreen® Dye: The Swiss Army Knife of qPCR
Biotium | Mar 1, 2024 | 7 min read
A green fluorescent dye with a novel DNA binding mechanism improves signal-to-noise in different DNA amplification assays.
TSS
Smart Gateways into the Lab of the Future
The Scientist | Sep 21, 2023 | 2 min read
Neurobiologists, computer scientists, and engineers join forces to grow mini brains using automation and make their technologies smarter with artificial intelligence.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
A Flood in Genomics
Brendan Maher | Nov 25, 2001 | 9 min read
Nine months have passed since draft sequences of the human genome were first published.1,2 One human gestation period later, the genome, as deciphered by the International Human Genome Sequencing Consortium, still screams toward its projected Spring 2003 finish date. "The trajectory we're on for meeting that goal is precisely on target," assures Francis Collins, director, National Human Genome Research Institute (NHGRI) and spokesperson for the largest public biological science project in histor
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Seafloor to bench top
Bob Grant | Oct 1, 2007 | 2 min read
A digital model of two of the "synaptic" proteins Kosik and his team found in a sponge's genome. Credit: Courtesy of The Public Library of Science (PLoS)" />A digital model of two of the "synaptic" proteins Kosik and his team found in a sponge's genome. Credit: Courtesy of The Public Library of Science (PLoS) Three years ago, Ken Kosik, a Harvard Medical School neurologist who studies Alzheimer disease, packed up files and equipment from his lab in Cambridge and moved 5,000 kilomete
Creative Emulsification
Sabrina Richards | Nov 1, 2012 | 8 min read
Enhancing data collection from emulsion PCR reactions: three case studies
Prospecting for Gold in Genome Gulch
Amy Adams | Apr 14, 2002 | 9 min read
The human genome is much like the American West of the 1850s: Everyone wants a piece of the pie. Similar to gold prospectors of 150 years ago, biotech and pharmaceutical companies, and even universities, are frantically searching for the nuggets of gold that will help them find the mother lode—a gene whose function is sufficiently marketable to make all of the preliminary research worthwhile. Companies that do strike gold get to introduce new classes of drugs to the market. Others hope to
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois
Beyond Sanger: Toward the $1,000 Genome
Aileen Constans | Jun 29, 2003 | 10 min read
Courtesy of Solexa Total Genotyping Without a doubt, the quarter-century-old Sanger sequencing method performed like a champ during the Human Genome Project. But with the capacity to read only a few hundred bases per reaction, it is far too slow and expensive for routine use in clinical settings. Reaping the rewards of the genomics era will clearly require faster and cheaper alternatives. Some companies estimate that within the next five years, technical advances could drop the cost of seque

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