Ricki Lewis | Jun 6, 2004 | 6 min read
PROFILING AN ESCAPEE:In A, cellular peptide binding assays of the wild-type p11C peptide and the mutant peptide (p11C*) for the MHC class i molecule Mamu-a*01 show reduced recognition for the mutant. The p11B peptide serves as an irrelevant control. In B, functional interferon g assays done on cell lines from monkeys 893, 833, and 798 show reduced response to peptide p11C in monkey 798 52 weeks after challenge.Clinical research by nature begets clichés: ups and downs, one step forward, one