ADVERTISEMENT

404

Not Found

Is this what you were looking for?

tag transcription factors immunology cell molecular biology

A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Kamal Nahas, PhD | Mar 15, 2024 | 4 min read
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
M. Horikoshi, C.K. Wang, H. Fujii, J.A. Cromlish, et al., "Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box," Nature, 341, 299-303, 28 September 1989. Masami Horikoshi (Rockefeller University, New York): "This paper describes the cloning of the gene encoding the TATA box [a conserved sequence of bases]-binding factor TFIID [transcription factor IID], which we and others have shown to be a key factor in both basic promoter
Molecular Biology
The Scientist Staff | Nov 8, 1992 | 2 min read
L.D. Kerr, J.-I. Inoue, N. Davis, E. Link, et al., "The Rel- associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation," Genes & Development, 5:1464-76, 1991. Lawrence Kerr (The Salk Institute, La Jolla, Calif.): "The regulation of protooncogene Rel, a transcription factor belonging to the family of NF-kB transcription factors, is important for the well-being of the cell because its altered form, v-rel, causes lymphoid leukemias. Wh
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
M.C. Schmidt, C.C. Kao, R. Pei, A.J. Berk, "Yeast TATA-box transcription factor gene," Proceedings of the National Academy of Sciences, 86, 7785-9, October 1989. Arnold Berk (University of California, Los Angeles): "TFIID binding to a TATA box initiates the ordered assembly of multiple transcription factors (TFs) required for initiation on eukaryotic promoters. However, TFIID resisted purification from higher organisms, preventing detailed studies of the process. We were interested in TFIID be

Run a Search

ADVERTISEMENT