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image: Silencing Surprise

Silencing Surprise

By | June 1, 2015

A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.

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Preliminary results from the Genotype-Tissue Expression project reveal that gene expression varies more across tissues than across individuals.

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image: Rethinking Telomeres

Rethinking Telomeres

By | March 1, 2015

Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.

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image: Similarities and Differences

Similarities and Differences

By | November 21, 2014

Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.

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image: Enhanced Enhancers

Enhanced Enhancers

By | November 1, 2014

The recent discovery of super-enhancers may offer new drug targets for a range of diseases.

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image: Thomson Reuters Predicts Nobelists

Thomson Reuters Predicts Nobelists

By | September 25, 2014

Using citation statistics, the firm forecasts which researchers are likely to take home science’s top honors this year.

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image: Trisomy 21 Effects Seen Genome-wide

Trisomy 21 Effects Seen Genome-wide

By | April 16, 2014

The extra chromosome behind Down’s syndrome can impact transcriptional regulation beyond chromosome 21, a study finds.

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image: Genomic Methylation Collector

Genomic Methylation Collector

By | October 22, 2012

A parasitic worm accumulates epigenetic DNA tags over its lifetime.  

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image: DNA with a Twist

DNA with a Twist

By | September 13, 2012

Researchers show that DNA supercoils are dynamic structures that can “hop” long distances, a phenomenon that could affect gene regulation.

5 Comments

image: The Sugar Lnc

The Sugar Lnc

By | May 1, 2012

Genes that react to cellular sugar content are regulated by a long non-coding RNA via an unexpected mechanism

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