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tag ras neuroscience

The Tiniest of Life's Rafts
Jill Adams | Oct 10, 2004 | 6 min read
LIPID RAFTS INSIDE AND OUT:© 2002 AAASIn the outer leaflet (A), sphingolipids and cholesterol form less fluid microdomains (B) called lipid rafts, which are enriched for GPI-proteins. Microdomains may contain more rigid subdomains (C) enriched for the sphingolipid ganglioside GM1. The membrane inner leaflet contains microdomains (D) with unknown lipid composition enriched for prenylated proteins. In contrast, caveolin and proteins carrying the two saturated fatty acyl chains become concentr
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l
Citation Analysis Identifies 1994's Most-Cited Authors, Hottest Topics
The Scientist Staff | May 28, 1995 | 8 min read
Editor's Note: Since 1993, the newsletter Science Watch has ranked the year's most cited scientists and research papers. Based on records compiled by the Philadelphia-based Institute for Scientific Information (ISI), analysts prepared such rosters for 1994. Researchers are ranked by their number of "hot papers." An article is considered "hot" if it has garnered a substantially greater number of citations, within a two-year period, than other papers in similar disciplines. For instance, the 199

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