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A photo of a dish in which cells, which look like small dots, have been enlarged and stained to make them visible to the naked eye.
New Swelling Technique Makes Cells Visible to the Naked Eye
A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.
New Swelling Technique Makes Cells Visible to the Naked Eye
New Swelling Technique Makes Cells Visible to the Naked Eye

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.

techniques, cell & molecular biology

Q8W3K0, listed in the DeepMind database as a potential plant disease resistance protein from Arabidopsis thaliana
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021 | 3 min read
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Advances in Nucleic Acid Sequencing
The Scientist | 1 min read
Download this eBook to learn how new sequencing methods revolutionize genetics research!
a person in a white lab coat with a blue glove inserting a clear pcr tube into a which thermocycler while holding an orange box
Coronavirus Mutations Could Muddle COVID-19 PCR Tests
Jack J. Lee | May 17, 2021 | 4 min read
Researchers find that SARS-CoV-2 variants can evade primer-probe sets and recommend that diagnostic assays include multiple targets for reliability.
A Bright New Tool to Record Cellular Interactions
Lisa Winter | Apr 1, 2021 | 3 min read
The G-baToN prototype transfers GFP between cells, illuminating cell-cell contacts.
Lab-Grown Mouse Embryos Form Limbs and Organs
Lisa Winter | Mar 19, 2021 | 3 min read
The embryos completed one-third of their total gestation outside of a uterus.
neurological disorder, brain disease, Q&A, Alzheimer's disease, Parkinson's disease, multiple sclerosis, motor neuron disease, neurodegeneration, blood-brain barrier, sex
Sex of Human Cells Matters in Studying Neurological Disease
Amanda Heidt | Mar 18, 2021 | 5 min read
Authors of a new review urge researchers to consider how the chromosomal sex of a cell affects experiments in research on neurodegeneration.
Human Blastocyst-Like Structures Made in the Lab
Abby Olena, PhD | Mar 17, 2021 | 4 min read
Two new papers describe the generation of so-called blastoids, which could avoid the use of embryonic cells and make studying early human development much more accessible.
COVID-19, SARS-CoV-2, pandemic, research, reverse genetics, toolkit, antibodies, RNA
Q&A: A Molecular Toolkit to Build SARS-CoV-2 Research Capacity
Asher Jones | Mar 3, 2021 | 6 min read
Sam Wilson discusses a user-friendly set of resources that he and his collaborators developed to aid labs pivoting to study COVID-19.
2021 life science predictions innovations biotech mrna single-cell sequencing diagnostics
Experts Predict the Hottest Life Science Tech in 2021 and Beyond
Bob Grant | Feb 1, 2021 | 7 min read
Last year’s Top 10 Innovations judges look into their crystal balls.
red blood cell rbc ipsc induced pluripotent stem cell blood tranfsuion bioreactor
New Protocol Advances Toward Lab-Made Universal Red Blood Cells
Diana Kwon | Dec 17, 2020 | 4 min read
Researchers report a new way of generating the cells from induced pluripotent stem cells in hopes they will one day be used in blood transfusions.
DeepMind AI Speeds Up the Time to Determine Proteins’ Structures
Lisa Winter | Dec 2, 2020 | 2 min read
The technology solves proteins’ 3-D shapes in minutes, when traditional methods may take years.
heath hen Tympanuchus cupido de-extinction grouse pgc germline transmission cultured germ cell transmission
The Booming Call of De-extinction
W. S. Roberts | Oct 19, 2020 | 6 min read
Scientists seek to combine genome editing with a technique used in chicken breeding to try to bring back lost birds.
Electric and Magnetic Field Treatments Lower Mouse Blood Sugar
Abby Olena, PhD | Oct 9, 2020 | 3 min read
The effects seem to be mediated by a reactive oxygen species in the animals’ livers.
Obituary, University of Oregon, Biochemistry, Molecular Biology, chromatin, chromatin reordering, chromatin reprogramming,
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020 | 3 min read
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
CRISPR, Cas-9, Nobel, Chemistry
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020 | 4 min read
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
Ibrahim Cissé’s Tools Provide a Lens to Watch RNA Production
Jef Akst | Sep 1, 2020 | 3 min read
The MIT physicist has demonstrated the importance of clusters of RNA polymerase and other transcription mediators in regulating RNA production.
Infographic: Transfection by Precision Cell Piercing
Ruth Williams | Apr 1, 2020 | 1 min read
A microfluidic device creates a single hole in each cell to allow efficient DNA entry without compromising viability.
Precision Membrane Puncture Enables Efficient Cell Transfection
Ruth Williams | Apr 1, 2020 | 3 min read
A device for piercing individual holes in cell membranes allows vector-free DNA delivery while maintaining cell viability.
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