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image: CRISPR–Enabled Epigenome Editing

CRISPR–Enabled Epigenome Editing

By | April 6, 2015

Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By | April 1, 2015

A guide to glycan microarrays

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Stimulating Neurons with Light and Gold

Stimulating Neurons with Light and Gold

By | March 12, 2015

Researchers develop a technique to trigger neural activity in culture using light to heat gold nanoparticles.

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image: Tricky Transfections

Tricky Transfections

By | March 1, 2015

A combination of microinjection and electroporation inserts genes into hard-to-reach cells.

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image: Pushing the Limits

Pushing the Limits

By | February 1, 2015

A guide to the newest techniques for examining epigenetics in single cells

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image: Screening Goes In Silico

Screening Goes In Silico

By | February 1, 2015

Computational tools take some of the cost—and guesswork—out of drug discovery.

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image: Zooming In

Zooming In

By | January 20, 2015

To improve the reach of optical microscopy, researchers are enlarging the biological features they wish to view.

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image: Eye on the Fly

Eye on the Fly

By | January 1, 2015

Automating Drosophila behavior screens gives researchers a break from tedious observation, and enables higher-throughput, more-quantitative experiments than ever before.

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