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tag chronic pain culture immunology microbiology

2020 in Scientists’ Own Words
Abby Olena, PhD | Dec 23, 2020 | 5 min read
The world was rocked by the COVID-19 pandemic this year, but researchers rose to all manner of challenges.
The Search for Persisters
Amanda B. Keener | Aug 11, 2015 | 4 min read
Lyme disease–causing bacteria can outmaneuver antibiotics in vitro and manipulate the mouse immune system.
The Body’s Ecosystem
The Scientist | Aug 1, 2014 | 10+ min read
Research on the human microbiome is booming, and scientists have moved from simply taking stock of gut flora to understanding the influence of microbes throughout the body.
Viral Soldiers
Jyoti Madhusoodanan | Jan 1, 2016 | 10+ min read
Phage therapy to combat bacterial infections is garnering attention for the second time in 100 years, but solid clinical support for its widespread use is still lacking.
Supplement: Fine-Tuning Our Defenses
Anne Harding | May 1, 2007 | 8 min read
1 Nonetheless, treatment probably won't involve blocking any one pathway entirely. Instead, the best treatments will make slight modifications in several places. "The future is really novel pathways - to interact with novel pathways that offer the opportunity for different types of responses," says Brian Kotzin, vice president of medical sciences at Amgen in Thousand Oaks, Calif. Billions of Data Points Despite the potential undesirable con
Does Multiple Sclerosis Have a Herpesvirus Connection?
Douglas Steinberg | May 1, 2000 | 9 min read
Editor's Note: This is the second of two articles on the difficulties of proving that a virus contributes to a disease. The first article, on mouse mammary tumor virus and human breast cancer, appeared in the April 17 issue of The Scientist.1 Donald R. Carrigan and Konstance K. Knox Someone once said that if you want to ruin your reputation, go into MS [multiple sclerosis] research, quips Jacqueline E. Friedman, a senior research associate at Rockefeller University. But Friedman, who deals wit
Researchers Finding Rewarding Careers As Software Entrepreneurs
Karen Hopkin | Jul 7, 1996 | 10 min read
Bacterium SIZE MATTERS: Deer ticks -- vectors of Borrelia Burgdorferi -- are half the size of the common dog tick, which is not associated with Lyme disease. As a new generation of adolescent deer tick enjoys its first blood meal, scientists in the United States and abroad continue to focus their research efforts on understanding and preventing Lyme disease. Ticks infected with the bacterium Borrelia burgdorferi cause more than 10,000 cases of Lyme disease in the U.S. each year, according to
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l

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