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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: Image of the Day: Lysosomes Go Traveling

Image of the Day: Lysosomes Go Traveling

By | August 8, 2017

To chew up waste in far-reaching dendritic spines, lysosomes are trafficked sometimes hundreds of microns away from the cell bodies of neurons in rats. 

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image: A Database of Genetic Differences Among Lab Mice

A Database of Genetic Differences Among Lab Mice

By | August 7, 2017

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Final Nail Hammered into NgAgo Coffin

Final Nail Hammered into NgAgo Coffin

By | August 3, 2017

The paper describing the gene-editing method is retracted.

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image: Details Published on CRISPR-treated Embryos

Details Published on CRISPR-treated Embryos

By | August 2, 2017

Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.

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image: Scientists Destroy Entire Chromosome with CRISPR

Scientists Destroy Entire Chromosome with CRISPR

By | August 1, 2017

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

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image: Human Genetic Variation May Complicate CRISPR

Human Genetic Variation May Complicate CRISPR

By | July 31, 2017

Slight sequence differences confound target sites in precision genome-editing, a study shows.

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image: Zebrafish Embryos Survive Deep Freeze and Quick Thaw

Zebrafish Embryos Survive Deep Freeze and Quick Thaw

By | July 28, 2017

In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.

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