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a section of a rat brain is imaged in dull green. a much brighter green human organoid takes up a large portion of the left side of the brain.
Researchers Transplant Human Neurons into Rat Brains
The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.
Researchers Transplant Human Neurons into Rat Brains
Researchers Transplant Human Neurons into Rat Brains

The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.

The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.

drug testing

Illustration of bacteriophages infecting a bacterium
Phages Treat Gut Inflammation in Mice
Andy Carstens | Aug 4, 2022 | 5 min read
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
A conceptual 3D illustration of motor neurons degrading
Canada Approves Experimental ALS Therapy
Andy Carstens | Jun 14, 2022 | 3 min read
The country’s provisional go-ahead could increase pressure already being exerted on the US Food and Drug Administration to approve the therapy.
Strat-M® Transdermal Diffusion Membrane 
The Scientist | 1 min read
For topical and transdermal delivery of pharmaceuticals and cosmetics.
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A 3-D Tumor Microenvironment for Personalized Immunotherapy
Roni Dengler, PhD | Sep 10, 2021 | 2 min read
A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.
Blue stethoscope resting on a pile of folders filled with papers
Ivermectin (Still) Lacks Scientific Support as a COVID-19 Drug
Catherine Offord | Aug 2, 2021 | 3 min read
A Cochrane review bolsters scientists’ advice that ivermectin should not be used against the disease outside of clinical trials, while a study claiming to have found beneficial effects in patients was withdrawn following allegations of data manipulation.
FDA Pulls Emergency Use Authorization for Antimalarial Drugs
Amanda Heidt | Jun 16, 2020 | 2 min read
Hydroxychloroquine and chloroquine, once thought to be promising COVID-19 treatments, come with serious heart risks.
Infographic: How to Catch Cheating Athletes
Anna Azvolinsky | Sep 1, 2019 | 3 min read
Anti-doping agencies are tracking levels of various molecules in athletes’ blood and urine over time to increase their ability to detect drug misuse.
The Race to Nab Cheating Athletes
Anna Azvolinsky | Sep 1, 2019 | 10+ min read
Anti-doping organizations are constantly developing new tests to catch athletes trying to boost their performance in increasingly sophisticated ways.
Genetically Personalized Fruit Flies Screen for Cancer Drugs
Ruth Williams | May 22, 2019 | 4 min read
Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.
hair analysis drug testing forensics doping test
Technique Improves Use of Hair for Drug Tests
Chia-Yi Hou | May 15, 2019 | 3 min read
Researchers develop a washing method that is better at removing drugs that have contaminated hair from the outside than existing protocols.
Tumor Organoids Predict How Well Patients Respond to Cancer Drugs
Ruth Williams | Feb 22, 2018 | 3 min read
Testing treatments on mini tumors may save time in identifying which therapies work best, a new study shows.   
Opinion: Improving FDA Evaluations Without Jeopardizing Safety and Efficacy
John D. Loike and Jennifer Miller | Feb 1, 2017 | 4 min read
What can be done to lower development costs and drug prices?
Repurposing Existing Drugs for New Indications
Anna Azvolinsky | Jan 1, 2017 | 10+ min read
An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.
Will Organs-in-a-Dish Ever Replace Animal Models?
Tanya Lewis | Jul 19, 2016 | 4 min read
Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say. 
Desperately Seeking Shut-Eye
Anna Azvolinsky | Mar 1, 2016 | 7 min read
New insomnia drugs are coming on the market, but drug-free therapy remains the most durable treatment.
Personalized Devices Predict Cancer Drug Response
Anna Azvolinsky | Apr 22, 2015 | 4 min read
Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.
Unauthorized HIV Trial Leader Fined
Bob Grant | Feb 3, 2014 | 2 min read
A Spanish researcher faces a penalty after conducting a study for which he never obtained proper approvals or insurance.
Ketamine Alternative Shows Promise
Abby Olena, PhD | Oct 16, 2013 | 2 min read
Researchers show that lanicemine is an effective antidepressant without the adverse effects of the related hallucinogenic drug.
Spinning Clinical Trials
Dan Cossins | Jan 16, 2013 | 1 min read
Results of breast cancer drug trials are regularly spun to conceal bias and make the drugs seem more effective or less toxic than they really are.
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