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Thwarting AAV-Neutralizing Antibodies Could Improve Gene Therapy
Emma Yasinski | Sep 25, 2020 | 5 min read
Adeno-associated viral vectors can deliver gene therapies, but AAV-neutralizing antibodies might prevent the medicines from working.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Senior Scientists Quit Europe
Silvia Sanides | Jun 1, 2003 | 7 min read
©Paul Barton, Corbis Rigid retirement policies are prompting scientists to flee Europe at the height of their professional lives to start second careers in the United States. Many of these researchers are still conducting experiments and are in no mood to slow down. But because nearly all European universities are government run, professors are left little choice when they reach mandatory retirement age, which in most countries is 65 years or even younger. Some scientists leaving for the
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Week in Review: October 5–9
Tracy Vence | Oct 8, 2015 | 2 min read
This year’s Nobel Prizes; toward developing a brown fat-activating drug; certain antioxidants can increase the spread of melanoma in mice; anonymity and post-publication peer review
Frontlines
Harvey Black | Mar 17, 2002 | 6 min read
Efforts to keep Russian scientists fully employed, thus away from countries seeking their expertise in making weapons of mass destruction, seem to be bearing fruit, according to Victor Alessi, president and CEO of the Arlington, Va.-based US Industry Coalition (USIC). Of 120 scientific projects in development, 27 are biology related. One such effort is the development of a high-speed needleless injector. The US Food and Drug Administration has approved the Russian design, and the injector should
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Going Viral
Breeann Kirby and Jeremy J. Barr | Sep 1, 2013 | 10+ min read
From therapeutics to gene transfer, bacteriophages offer a sustainable and powerful method of controlling microbes.
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a
Enzymology's New Frontiers
Mark Greener(biowriter@markgreener.fsnet.co.uk) | Jan 18, 2004 | 10+ min read
Investigators are learning about structures and rethinking old theories

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