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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Happenings
The Scientist Staff | Aug 9, 1987 | 4 min read
Robert Hoffmann, director of the Smithsonian Institution’s National Museum of Natural History, has been named Assistant Secretary for Research, effective January 1, 1988. Prior to joining the Smithsonian staff, Hoffmann was Summerfield Distinguished Professor at the University of Kansas, Lawrence, and curator of mammals at the University of Kansas Museum of Natural History. As assistant secretary, Hoffmann will serve as the principal adviser to the secretary and undersecretary on the Smit
Science Museums Exhibit Renewed Vigor
Christine Bahls | Mar 28, 2004 | 10+ min read
Erica P. JohnsonApreschool girl with black braids presses a finger to a disk that twists a brightly lit DNA model, transforming its ladder shape into a double helix. Her head bops from side to side in wonder as the towering DNA coils and straightens. When a bigger boy claims her place, the girl joins meandering moms and dads with their charges as they twist knobs, open flaps, and simply stare at flashing helixes and orange information boards: all a part of the museum exhibit called "Genome: The
bob murphy
Robert Murphy Bets Self-Driving Instruments Will Crack Biology’s Mysteries
Shawna Williams | May 1, 2019 | 9 min read
The Carnegie Mellon computational biologist thinks machine learning algorithms can direct high-throughput experiments to solve the field’s unanswered questions.
2011 World Science Festival: A look back
The Scientist | Jun 10, 2011 | 5 min read
The Scientist covered some of the events that made this year's festival memorable.

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