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image: Bacteriophages to the Rescue

Bacteriophages to the Rescue

By | July 17, 2017

 Phage therapy is but one example of using biological entities to reduce our reliance on antibiotics and other failing chemical solutions.

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image: Book Excerpt from <em>Natural Defense</em>

Book Excerpt from Natural Defense

By | July 17, 2017

In Chapter 3, “The Enemy of Our Enemy Is Our Friend: Infecting the Infection,” author Emily Monosson makes the case for bacteriophage therapy in the treatment of infectious disease.

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image: Ancient Protein Helps <em>E. coli</em> Thwart Viral Attack

Ancient Protein Helps E. coli Thwart Viral Attack

By | May 9, 2017

When engineered to use a four-billion-year-old version of the protein thioredoxin, the bacteria can stall bacteriophage replication, a new study shows.

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image: More Anti-CRISPR Proteins to Block Cas9

More Anti-CRISPR Proteins to Block Cas9

By | December 29, 2016

The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.

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image: Keeping CRISPR in Check

Keeping CRISPR in Check

By | December 14, 2016

In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells. 

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image: Phages Carry Antibiotic Resistance Genes

Phages Carry Antibiotic Resistance Genes

By | December 8, 2016

Researchers find evidence of antibiotic resistance genes in the DNA of viruses that infect bacteria.

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image: Black Widow Secrets in Phage Genome

Black Widow Secrets in Phage Genome

By | October 12, 2016

In the DNA of the WO phage, which infects arthropod-inhabiting Wolbachia, researchers find sequences related to a black widow spider’s toxin and other animal genes.

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image: Protein or Perish

Protein or Perish

By | September 1, 2016

A bacteriophage must evolve certain variants of a protein or die.

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image: CRISPR Antidotes Galore

CRISPR Antidotes Galore

By | June 13, 2016

Anti-CRISPR proteins are prevalent in phage genomes and bacterial mobile genetic elements, researchers show.

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image: Lu on Syn Bio

Lu on Syn Bio

By | May 1, 2016

MIT researcher and Scientist to Watch Timothy Lu talks about the value of cross-disciplinary approaches in bringing synthetic biology into the clinic.

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