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tag neglected tropical diseases evolution genetics genomics

Cartoon of scientist deciding whether to go down the path of well-studied genes or that of the neglected genes. 
Stepping Into the Unknome
Danielle Gerhard, PhD | Mar 8, 2024 | 5 min read
A database of neglected genes may help unlock the mysteries hiding in the overlooked regions of the proteome.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
Uncovering Leprosy’s Genetic Recipe for Success
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD | Aug 17, 2022 | 3 min read
Researchers identify what makes certain people more likely to contract leprosy than others.
A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.
New Drug Target for Three Tropical Diseases
Tracy Vence | Aug 9, 2016 | 1 min read
Researchers efficiently clear mice of the parasites that cause leishmaniasis, Chagas disease, and sleeping sickness by inhibiting the parasites’ kinetoplastid proteasomes.
Fluorescent images of red cells showing high and low levels of infection in green
Parasite Drove Natural Selection in Amazonian Indigenous Groups
Natalia Mesa, PhD | Mar 13, 2023 | 4 min read
The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
A desert locust (Schistocerca gregaria) on sand
Genome Spotlight: Desert Locust (Schistocerca gregaria)
Christie Wilcox, PhD | Jul 21, 2022 | 4 min read
A chromosome-scale genome sequence for this infamous agricultural pest could help mitigate its plagues.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

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