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tag alternative splicing ecology genetics genomics immunology microbiology

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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Premade cDNA Libraries
Sarah Goforth | Apr 15, 2001 | 10 min read
Suppliers of Whole-organism cDNA Libraries Suppliers of Tissue-specific cDNA Libraries The questions of gene function, interaction, and regulation are central to the science of molecular biology. Despite the myriad of new technologies, products, and techniques produced by the genomics revolution, some old standards remain just as useful as ever. One such technology is the cDNA (complementary DNA) library. The sheer number of companies offering premade and custom cDNA libraries and products th
Probing Protein Interactions
Laura Defrancesco | Apr 14, 2002 | 8 min read
The challenge of proteomics is personified in the Greek god, Proteus. The keeper of all knowledge, past, present and future, Proteus would not give up any information easily; even while held down, he would struggle and assume different forms before giving anything up. Remarkably, proteomics, and proteins for that matter, were not named after Proteus, but the imagery could not be more fitting. It's still anyone's guess what the final gene count will be in the human genome, let alone the total nu
GM Crops Face Heat Of Debate
Ricki Lewis | Oct 10, 1999 | 10+ min read
For a successful technologyReality must take precedence over public relations, for nature cannot be fooled. --Richard Feynman Nobel physicist Richard Feynman was talking about the role NASA and its industrial partners played in the 1986 Challenger disaster, but his words could easily apply to the debate over genetically modified (GM) crops. When grain processor Archer Daniels Midland (ADM) of Decatur, Ill., asked suppliers on Sept. 2 to segregate GM corn from traditional varieties, some U.S. b
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a
Bioengineered Bugs A 'Brisk Trade' In Applied and Basic Entomology
Karen Young Kreeger | Sep 17, 1995 | 7 min read
if (n == null) The Scientist - Beyond the Fruit Fly The Scientist 9[18]:13, Sep. 18, 1995 Research Beyond the Fruit Fly By Karen Young Kreeger Of all the animal species described thus far by scientists, insects account for nearly five-sixths. Nearly 1 million are already identified, with taxonomists estimating another 1 million to go. Despite their ubiquity on Earth, the study of insects has only recently been married to the explosion of molecular biologic
Articles Alert
Frank Wilczek | Jul 9, 1989 | 7 min read
PHYSICS >BY FRANK A. WILCZEK School of Natural Sciences Institute for Advanced Study Princeton, NJ. " A special issue of Progress of Theoretical Physics is devoted to a broad consideration of a classic and still fascinating problem. Research Institute for Fundamental Physics and The Physical Society of Japan, “Origin of the solar system,” Progress of Theoretical Physics (Supplement), 96, 1-3 19, 1988. (Kyoto University, Japan) " This year’s Henry Norris Russell Lecture rev
Enzymology's New Frontiers
Mark Greener(biowriter@markgreener.fsnet.co.uk) | Jan 18, 2004 | 10+ min read
Investigators are learning about structures and rethinking old theories

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