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image: Double-Edged Enzyme

Double-Edged Enzyme

By | August 13, 2015

Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.

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image: The Dark Side of Melanin

The Dark Side of Melanin

By | February 19, 2015

Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.

5 Comments

image: Oocytes and Obesity

Oocytes and Obesity

By | February 10, 2015

Eggs from excessively overweight mothers suffer mitochondrial damage that can be averted with pharmacological intervention, a mouse study finds. 

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image: Gut Microbes Trigger Malaria-Fighting Antibodies

Gut Microbes Trigger Malaria-Fighting Antibodies

By | December 4, 2014

A carbohydrate antigen found on cells of E. coli and other species prompts a potent immune response against malaria-causing parasites in mice.

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image: Lab Versus House Mouse

Lab Versus House Mouse

By | August 21, 2014

Some behavioral traits, like female aggression, were lost with domestication, a study shows.

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

4 Comments

image: Fixing Protein Folding

Fixing Protein Folding

By | December 9, 2013

A small molecule that stabilizes a misfolded receptor can treat symptoms of a genetic mutation in mice, researchers show.

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image: Do Mice Make Bad Models?

Do Mice Make Bad Models?

By | February 11, 2013

A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.

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image: Genome Digest

Genome Digest

By | November 13, 2012

What researchers are learning as they sequence, map, and decode species’ genomes

2 Comments

image: Lab Rats Need Better Diets

Lab Rats Need Better Diets

By | July 18, 2012

Rodents fed all-you-can-eat diets may be skewing experimental results.

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