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tag defense culture genetics genomics immunology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
Immune Genes Protect Cells from Ebola Virus and SARS-CoV-2
Rachael Moeller Gorman | Dec 1, 2020 | 3 min read
A pathway involved in the adaptive immune system, a relative newcomer in the world of pathogen defense, may have a more ancient role in protecting cells from invading viruses.
Supplement: Fine-Tuning Our Defenses
Anne Harding | May 1, 2007 | 8 min read
1 Nonetheless, treatment probably won't involve blocking any one pathway entirely. Instead, the best treatments will make slight modifications in several places. "The future is really novel pathways - to interact with novel pathways that offer the opportunity for different types of responses," says Brian Kotzin, vice president of medical sciences at Amgen in Thousand Oaks, Calif. Billions of Data Points Despite the potential undesirable con
Researchers Learn from Plant Viruses to Protect Crops
Claire Asher | Feb 1, 2018 | 10+ min read
Plants are locked in an ancient arms race with hostile viruses, but genome editing is giving crops the upper hand.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021 | 10+ min read
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
Exosomes Make Their Debut in Plant Research
Amanda Keener | Feb 1, 2019 | 10+ min read
A growing branch of research on how plants use exosomes to interact with their environment is opening up a new field of plant biology.

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