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tag pluripotency immunology developmental biology culture

3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Human Pluripotent Cells Pass Safety Test
Douglas Steinberg | Sep 1, 2002 | 7 min read
Image: ©2001 MacMillan Publishers Ltd.  PLURIPOTENT-CELL PIPELINE: To obtain embryonic germ cells, researchers culture primordial germ cells (PGCs) dissected from the genital ridge. If left in situ, a PGC develops into spermatozoa or ova after its imprints have been erased and reestablished. Embryonic stem cells come from the blastocyst's inner cell mass. (Reprinted with permission, Nature 414:122-8, 2001) Because the science is hard and the politics mean, progress in understanding
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Flow Cytometry for the Masses
Richard P. Grant | Dec 1, 2011 | 2 min read
Tagging antibodies with rare earth metals instead of fluorescent molecules turns a veteran technique into a high-throughput powerhouse.
The Many Model Systems of COVID-19
Abby Olena, PhD | Nov 4, 2020 | 7 min read
Researchers turn to familiar model animals, along with some fresh strategies, to develop countermeasures against SARS-CoV-2 and investigate the biology of infection.
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Toward Preventing Transplant Rejection with Immunologically Matched Stem Cells
Ruth Williams | Sep 15, 2016 | 3 min read
Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.
Top 7 papers in cell biology
Jef Akst | Dec 5, 2010 | 3 min read
Just in time for ASCB -- see the cell biology articles most highly ranked by F1000

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