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tag pluripotency disease medicine immunology cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Macrophages on the Fast Track to Tumor Defense
Laura Tran, PhD | Feb 22, 2024 | 3 min read
In a race to the tumor, a macrophage’s phenotype can give it a leg up on the competition.
Leveraging Stem Cells to Create Better Disease Models
Leveraging Stem Cells to Create Better Disease Models
The Scientist | May 29, 2023 | 2 min read
Clive Svendsen, Meritxell Huch, Ameen Salahudeen, and Maksim Plikus will discuss the latest advances in using patient-derived stem cells to create more accurate disease models.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker, PhD | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
Immunology
The Scientist Staff | Apr 2, 1995 | 2 min read
Edited by: Neeraja D. Sankaran R.M. Chicz, R.G. Urban, J.C. Gorga, D.A.A. Vignali, W.S. Lane, J.L. Strominger, "Specificity and promiscuity among naturally processed peptides bound to HLA-Dr alleles," Journal of Experimental Medicine, 178:27-47, 1993. (Cited in 107 publications through January 1995) Comments by Roman M. Chicz,department of molecular and cellular biology, Harvard University One of the most important findings in this article, according to its authors, was the observation of pr
A person lying on a bed checks the reading on a digital thermometer. A table with a bowl of oranges and various medications is in the background.
How Mild Is Omicron Really?
Dan Robitzski | Jan 14, 2022 | 9 min read
Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.

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