From basic research to beneficial therapies
Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.
A group of microRNAs can inhibit the formation of induced pluripotent stem cells, and may provide a target for more efficient reprogramming of somatic cells.
Researchers are developing ways to convert mature somatic cells from one cell type to another, avoiding the tumor-causing pluripotent stage associated with stem cells.
Cells derived from embryonic and induced pluripotent stem cells exhibit striking differences from the cells they’re supposed to represent.
A new antibody cocktail can remove undifferentiated, tumor-forming cells from a mix of embryonic stem cells.
Researchers discover a protein that may allow already-differentiated somatic cells to become stem cells
Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.
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