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tag cell death microbiology cell molecular biology disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Combating COVID-19 with Cell-Free Expression
The Scientist | Aug 19, 2020 | 6 min read
Scientists rely on synthetic biology and cell-free expression systems for developing novel approaches to combat the pandemic.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Epithelial cells and fungal spores are marked with fluorescent dyes. Cells have an irregular shape and are shown in green and blue colors. Spores are spherical in shape and are labeled green if they are surrounded by p11 protein. A protein in mature phagosomes is labeled violet.
Fungal Spores Hijack a Host Protein to Escape Death
Mariella Bodemeier Loayza Careaga, PhD | Jun 20, 2023 | 3 min read
Uncovering the components used by Aspergillus fumigatus to avoid intracellular destruction broadens our understanding of the mold’s pathogenesis. 
Four glass vials sit on a reflective tabletop next to a syringe. Each is labeled as a subsequent dose in a four-dose series of COVID-19 vaccines.
What We Know About Getting a Second Booster Shot of COVID-19 Vaccines
Dan Robitzski | Aug 11, 2022 | 10+ min read
Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.
Gene Splicing Pioneer Dale Kaiser Dies
Ashley Yeager | Jun 29, 2020 | 5 min read
Working with a virus that infects bacteria, the Stanford University biochemist and developmental biologist helped to develop a way to stitch DNA together, a discovery that gave rise to genetic engineering.
Cross section of an organic cell with intracellular organelles
How Intracellular Bacteria Hijack Your Cells
Catherine Offord | Dec 1, 2022 | 10+ min read
Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.
Top 7 cell biology papers
Jef Akst | Jul 12, 2010 | 3 min read
#1 Gene for autoimmunity Rare genetic variants in the protein sialic acid acetylesterase (SASE) are linked to common human autoimmune diseases, including type 1 diabetes, arthritis, and Crohn's disease. In mice, defects in the protein have been linked to problems in B-cell signaling and the development of auto-antibodies. I. Surolia, et al., "Functionally defective germline variants of sialic acid acetylesterase in autoimmunity," Nature, 466:243-7. Epub 2010 Jun 16. linkurl:Eval;http://f1000b
A person lying on a bed checks the reading on a digital thermometer. A table with a bowl of oranges and various medications is in the background.
How Mild Is Omicron Really?
Dan Robitzski | Jan 14, 2022 | 9 min read
Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.
The Scientist Staff | Mar 28, 2024

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