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tag in vitro fertilization ivf evolution genetics genomics disease medicine

Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next
Opinion: Don’t Ban the Use of CRISPR in Embryos
John D. Loike | Nov 29, 2018 | 2 min read
Despite a premature and ethically sketchy claim of genome editing in twin girls, an outright prohibition could blunt promising, responsible progress.
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois
Notebook
The Scientist Staff | Feb 15, 1998 | 8 min read
POSITIVE SIDE EFFECT Proposed legislation designed to ban genetic discrimination may boost participation in clinical trials, says Kathy L. Hudson, assistant director for policy coordination at the National Human Genome Research Institute. Vice President Al Gore issued guidelines for genetic discrimination legislation in a report entitled "Genetic Information and the Workplace" January 20 at the National Academy of Sciences. The legislation, if enacted, would bar employers from using genetic mak
Opinion: Ethical Considerations of “Three-Parent” Babies
John D. Loike and Nancy Reame | Dec 22, 2016 | 4 min read
Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.
Three-Way Parenthood
Yehezkel Margalit, John D. Loike, and Michio Hirano | Oct 1, 2013 | 4 min read
Avoiding the transmission of mitochondrial disease takes a trio, but raises a host of logistical issues.
Week in Review: January 27–31
Tracy Vence | Jan 31, 2014 | 3 min read
Stimulus-triggered pluripotency; antioxidants speed lung tumor growth; the importance of seminal vesicles; how a plant pathogen jumps hosts

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